Common types of cancer

Prostate Cancer

Common types of cancer

Prostate Cancer

What is Prostate Cancer? Anatomy and Function

The prostate is part of a man’s reproductive system. It is located in front of the rectum and behind the bladder. Urine flows through the urethra, which is surrounded by the prostate. The prostate is a gland that secretes seminal fluid. During ejaculation, seminal fluid facilitates the removal of sperm from a man's body as part of the semen.

The prostate is approximately the size of a walnut when it is healthy. In the case of an enlarged prostate, the urethra may be squeezed. As a result, the urine flow from the bladder to the penis may be slowed or stopped.

According to a published longitudinal study¹ on prostate cancer in multi-ethnic Asian men.

Men under 45 years of age are rarely diagnosed with prostate cancer. The rate increases sharply with age, reaching its peak among older people.

What are the Stages of Prostate Cancer?

01

Stage 1

Cancer is found only in the prostate, usually during another medical procedure. A digital rectal examination or imaging test is unable to detect it.

02

Stage 2

An imaging test cannot detect a tumour at this stage because it is too small to be felt or seen. It may also refer to a slightly larger tumour that can be detected during a Digital Rectal Examination. There is no evidence that cancer has spread beyond the prostate gland.

03

Stage 3

Cancer has spread beyond the outer layer of the prostate to nearby tissues. The disease may also spread to the seminal vesicles.

04

Stage 4

In this stage, the tumour has spread to other parts of the body, such as the bladder, rectum, bone, liver, lungs, or lymph nodes.

Risk Factors of Prostate Cancer

The exact cause of prostate cancer is unknown. In most cases, doctors cannot explain why one man develops prostate cancer while another does not. It has been shown, however, that men who possess certain risk factors are more likely than others to develop prostate cancer.

Over the age of 65

A person's age is the most significant risk factor for prostate cancer. As you age, your risk of developing prostate cancer increases. In men under the age of 45, this disease is rare.

History of the family

There is a higher risk of prostate cancer if your father, brother, or son has been diagnosed with the disease.

Race

Male Caucasians are more likely to develop prostate cancer than male Asians.

Diet

According to some studies, men who consume a diet high in animal fat or meat may be at an increased risk of prostate cancer. A diet rich in fruits and vegetables may reduce men’s prostate cancer risk.

Recognising Early Signs and Symptoms of Prostate Cancer

The first indication that a man may have prostate cancer is often an abnormal finding in his routine screening test. Others may notice one or more of the following lower tract symptoms which comprise of :

Difficulty passing urine

Difficulty passing urine

Slow urine stream or difficulty controlling the urine

Slow urine stream or difficulty controlling the urine

Waking up at night to pass urine

Waking up at night to pass urine

Back pain

Back pain

Weight loss

Weight loss

It is also possible that some of these symptoms indicate a common, non-cancerous condition called Benign Prostatic Hyperplasia (BPH), which is an enlargement of the prostate gland. If you experience any of these symptoms, you should seek medical attention as soon as possible to ensure proper diagnosis and treatment.

Man with pelvic pain, a common sign of prostate cancer.

Prostate Cancer Screening and Diagnostic Tests

The following clinical findings and laboratory tests can be used to diagnose prostate cancer:

Digital rectal examination

To determine if there are any abnormalities in your prostate, your doctor will examine it through the rectum.

Prostate Specific Antigen (PSA) level

PSA is a substance produced by the prostate to liquefy the semen. A higher level than normal may indicate the presence of cancer.

Multiparametric MRI (mpMRI)

Where suspicious tumours can be accurately located.

Transrectal ultrasound-guided biopsy or Transperineal MRI fusion biopsy

Once the suspicious tumours are located, they can be sampled either through the rectum using an ultrasound probe on its own or through needles piercing the perineum with targeting aided by the MRI which is more accurate.

Digital rectal examination

One of the most common types of cancer among men is prostate cancer. Various methods can be used to stage prostate cancer to determine the disease’s stage, such as CT, MRI, and bone scintigraphy. Galium-68 PSMA PET CT can be used to image the entire body and detect the spread of diseased tissue with high sensitivity. It has not been possible to observe early metastatic spread to lymph nodes and bones until recently. PSMA PET/CT is a cutting-edge diagnostic technology for locating and determining the extent of prostate cancer utilising galium-68. By using PSMA scans, therapy can be targeted more directly since lymph nodes, bones, and the prostate can be assessed.

To determine whether prostate cancer has spread, your doctor may perform scans of the pelvis and bone.

Making Decisions About Prostate Cancer Treatment

To successfully treat prostate cancer, a skilled multidisciplinary team must be assembled as numerous treatment options are available. To provide the most advanced treatment options for patients with early or advanced prostate cancer, SJMC brings together the most advanced resources available.

Our team of urologists, clinical oncologists, and radiologists created multidisciplinary treatment plans. Each of our doctors ensures that each patient is fully informed about factors such as the stage and grade of his tumour, the range of treatment options and possible side effects. A physician at this facility can assist patients in navigating the sometimes-complex choices presented by these factors.

Patient consults a doctor about prostate cancer treatment in Malaysia.

Advanced Prostate Cancer Treatment Options in Malaysia

Watchful Waiting

Watchful Waiting

Immediate treatment is unnecessary if prostate cancer is not advanced and slow growing. Based on the patient’s cancer characteristics, active surveillance will be recommended, deferring treatment for the time being while on close monitoring.

Radical Prostatectomy surgery for Prostate Cancer Treatment

Surgery

Also known as radical prostatectomy by surgically removing the prostate and the tissue surrounding it. Usually, a sample of lymph nodes nearby tissue will be removed to ascertain if cancer has spread beyond the prostate.

Systemic Therapies

Systemic Therapies

Combination of hormonal and chemotherapy. Hormonal therapy can also be combined with radiotherapy.

Radiation Therapy

Radiation Therapy

Radiation therapists use high-energy rays from an external beam (like an x-ray) or brachytherapy (implantation of radioactive seeds) to treat prostate cancer.

Advanced Techniques for Prostate Cancer Treatment at SJMC

SJMC's Cancer & Radiosurgery Centre is equipped with the sophisticated and highly advanced Tomotherapy Hi-ART system & Varian TrueBeam system.

TomoTherapy machine for advanced prostate cancer radiation treatment.

Helical Tomotherapy and Volumetric Arc Therapy (VMAT)

There was difficulty in targeting radiation beams precisely in the past, which caused harm to healthy tissues during cancer treatment; today, new systems used at SJMC have brought Radiation Therapy into the 21st century.

Helical tomotherapy combines three-dimensional imaging with innovative intensity-modulated radiation therapy, or IMRT, to primarily target the tumour while sparing nearby healthy tissues.

Varian TrueBeam system for precise prostate cancer radiotherapy.

Varian TrueBeam System

Using Varian TrueBeam STX technology, also known as RapidArc, Volumetric Arc Therapy (VMAT) delivers fast and accurate radiation treatment.

Prostate-Specific Membrane Antigen (PSMA) Therapy

Lutetium-177 PSMA Therapy, or Prostate-Specific Membrane Antigen Therapy, is an increasingly popular treatment for people with advanced prostate cancer. By using this therapy, the tumour will be reduced in size and will not multiply, as well as the symptoms associated with these tumours will be eased. Usually, it is used when the disease has metastasised, and other therapies have been ineffective or poorly tolerated.

Supportive Care for Prostate Cancer Patients

The staff and doctors of the Centre are dedicated to providing the best possible care for each individual. The goal is to enhance the well-being of all patients. All our patients have access to the Cancer & Radiosurgery Centre Patient and Family Resource Centre, which offers a wide array of support and educational services, including:

Oncology Nurse Educator
Patient & Family Liaison Officer
Counsellor
Pain management specialists
Cancer Careline
Post-surgery Stoma Care

Prostate Cancer Support Programmes at SJMC

Diet workshops

Support group activities

Yoga & Exercise workshops

Leading the Way in Prostate Cancer Care

SJMC Cancer & Radiosurgery Centre has been recognised for its leadership in cancer management.

This content aims to provide you with the necessary information and coping techniques to help you manage your cancer. However, this content should not be construed as medical advice. You must consult with a doctor before considering any treatment.

The staff members and doctors at the centre are dedicated to providing the best possible care for each patient and aim to enhance the patient's emotional and physical well-being. The facility also offers various support groups and other services to help ease the daily stress of living with cancer.

FAQs About Prostate Cancer

What is prostate cancer?

Prostate cancer is a malignant tumor that develops in the prostate gland, a small walnut-shaped organ in the male reproductive system responsible for producing seminal fluid. It is one of the most common types of cancer in men.

What are the early signs of prostate cancer?

Early signs include difficulty urinating, frequent urination at night, and a weak urine stream. Visit SJMC for screening and diagnosis.

How is prostate cancer diagnosed?

Diagnosis typically involves three primary steps: a Prostate-Specific Antigen (PSA) blood test, a Digital Rectal Exam (DRE) to check for physical abnormalities, and a prostate biopsy to extract tissue samples for laboratory confirmation.

The Four Stages of Prostate Cancer Explained

Prostate cancer stages range from Stage 1 to Stage 4:
• Stage 1: Cancer is small and confined entirely to the prostate.
• Stage 2: Cancer is larger but still confined to the prostate.
• Stage 3: Cancer has spread outside the prostate to nearby tissues (like seminal vesicles).
• Stage 4: Cancer has metastasized to distant organs, such as bones or the liver.

Common Prostate Cancer Causes and Risk Factors

The primary risk factors of prostate cancer include advancing age (most common in men over 65), family history (genetics), race, and lifestyle factors such as a diet excessively high in red meat or high-fat dairy products.

What are the symptoms of advanced prostate cancer?

Unlike early stages which primarily affect urination, advanced prostate cancer symptoms occur when the cancer spreads. These include severe bone pain (often in the spine, hips, or ribs), unexplained weight loss, extreme fatigue, and swelling in the legs or pelvic area.

What are the benefits of prostate cancer screening?

Early screening is crucial because prostate cancer often presents zero symptoms in its initial, most curable stages. For men in Malaysia, especially those over 50 or with a family history, routine PSA testing allows for early detection, which drastically increases the success rate of treatments and minimizes the need for aggressive surgeries.

What treatment options are available for prostate cancer?

Prostate cancer treatment depends on the cancer stage and may include: Watchful Waiting (Active Surveillance) for slow-growing tumors, Surgery (Prostatectomy) to remove the gland, Radiation Therapy (such as VMAT or Tomotherapy), and Systemic Therapies including hormone therapy, chemotherapy, or targeted PSMA therapy.

Why choose SJMC for prostate cancer care?

SJMC offers advanced diagnostic tools, cutting-edge treatments like PSMA therapy, and a multidisciplinary team to provide comprehensive prostate cancer care.

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